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Merck
CN

890810P

Avanti

18:0 DDAB

Avanti Research - A Croda Brand

别名:

双十八烷基二甲基铵(溴化盐)

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关于此项目

经验公式(希尔记法):
C38H80NBr
化学文摘社编号:
分子量:
630.95
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (890810P-1g), pkg of 1 × 200 mg (890810P-200mg), pkg of 1 × 25 mg (890810P-25mg), pkg of 1 × 500 mg (890810P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

application(s)

vaccine development

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

InChI key

PSLWZOIUBRXAQW-UHFFFAOYSA-M

General description

18:0 DDAB是阳离子脂质和季铵盐。与可电离的脂质不同,烃尾巴是饱和的。

Application

18:0 DDAB适合制备脂质纳米颗粒。它还可用作佐剂,与单磷酸脂A(MPL)联合用于免疫小鼠。

Biochem/physiol Actions

18:0 DDAB是一种表面活性分子,可用作诱导全身免疫反应的佐剂。无毒。

Packaging

20 mL透明玻璃螺旋盖样品瓶(890810P-1g)
20 mL透明玻璃螺旋盖样品瓶(890810P-500mg)
5 mL棕色玻璃螺旋盖样品瓶(890810P-200mg)
5 mL棕色玻璃螺旋盖样品瓶(890810P-25mg)

Other Notes

仅供研发使用。& 不可用于药物、家庭或其他用途。

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hong Yu et al.
Infection and immunity, 78(5), 2272-2282 (2010-03-17)
Major impediments to developing a Chlamydia vaccine lie in identifying immunologically relevant T-cell antigens and delivery in a manner to stimulate protective immunity. Using an immunoproteomic approach, we previously identified three immunodominant Chlamydia T-cell antigens (PmpG-1, PmpE/F-2, and RplF). Because
Lipophilic quaternary ammonium salt acts as a mucosal adjuvant when co-administered by the nasal route with vaccine antigens
Klinguer C, et al.
Vaccine, 19(30), 4236-4244 (2001)
Ana Cristina Norberto Oliveira et al.
ACS applied materials & interfaces, 6(9), 6977-6989 (2014-04-10)
This study describes a novel liposomal formulation for siRNA delivery, based on the mixture of the neutral lipid monoolein (MO) and cationic lipids of the dioctadecyldimethylammonium (DODA) family. The cationic lipids dioctadecyldimethylammonium bromide (DODAB) and chloride (DODAC) were compared in



全球贸易项目编号

货号GTIN
890810P-25MG04061835534098
890810P-1G04061835534074
890810P-200MG04061835534081