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Merck
CN

890880P

Avanti

18:0 TAP

Avanti Research - A Croda Brand

别名:

1,2-硬脂酰-3-三甲基铵-丙烷(氯化物盐)

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关于此项目

经验公式(希尔记法):
C42H84NO4Cl
化学文摘社编号:
分子量:
702.57
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (890880P-200mg), pkg of 1 × 25 mg (890880P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]

InChI key

NTTZBBIBMSBLNK-UHFFFAOYSA-M

Application

1,2-硬脂酰-3-三甲基铵-丙烷(18:0 TAP)可用于:
  • 通过薄膜水合技术制备三负载胆汁糖体(Tri-BLs)
  • 配制脂质纳米颗粒(LNP),以测试其将 mRNA 包装成 LNP 的效率
  • 制造单层空脂质体
  • 制备脂质复合物

Biochem/physiol Actions

1,2-硬脂酰-3-三甲基铵-丙烷(18:0 TAP)是一种用于 DNA 转染的阳离子脂质。

Packaging

5 mL棕色玻璃螺旋盖小瓶(890880P-200mg)
5 mL棕色玻璃螺旋盖小瓶(890880P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hailing Yang et al.
Drug delivery, 26(1), 820-830 (2019-08-08)
Arthritis treatment has been challenging because of low drug exposure to the articular cavity. This study was intended to develop hyaluronic acid (HA)-functionalized bilosomes for targeted delivery of tripterine (Tri), an antiphlogistic phytomedicine, to the inflamed joint via ligand-receptor interaction.
Maria Jose York-Duran et al.
Biomaterials science, 7(11), 4813-4826 (2019-09-20)
While ROS display crucial functions in many physiological processes, elevated ROS levels are also related to the initiation and progression of many severe diseases such as cancer, cardiovascular conditions or neurologic disorders. Research approaches to diminish ROS levels during disease
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)



全球贸易项目编号

货号GTIN
890880P-25MG04061835188505
890880P-200MG04061835188499