E-022
EDDP高氯酸盐标准液 CRM 溶液
1.0 mg/mL in methanol (as pyrolinium), ampule of 1 mL, certified reference material, Cerilliant®
别名:
美沙酮代谢产物
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关于此项目
经验公式（希尔记法）:
C20H24ClNO4
化学文摘社编号:
分子量:
377.86
UNSPSC Code:
41116107
MDL number:
NACRES:
NA.24
EC Number:
200-659-6
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol (as pyrolinium)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
SMILES string
C[N+]1=C(CC)C(C2=CC=CC=C2)(C3=CC=CC=C3)CC1C.O=Cl(=O)([O-])=O
InChI
1S/C20H24N.ClHO4/c1-4-19-20(15-16(2)21(19)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18;2-1(3,4)5/h5-14,16H,4,15H2,1-3H3;(H,2,3,4,5)/q+1;/p-1
InChI key
FICCBMGBBWWZRF-UHFFFAOYSA-M
General description
美沙酮主要尿液代谢产物的认证 Snap-N-Spike ® 溶液。美沙酮以各种商品名销售，如 Symoron、Amidone 或 Methadose ®，它是一种合成阿片类药物，在医学上用作镇痛剂和维持抗成瘾剂，用于阿片类药物依赖患者。该参照标准品的适当用途包括作为制备用于临床毒理学或法医学分析的 LC/MS 或 GC/MS 法的校准品和质控品的起始物料。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Methadose is a registered trademark of Mallinckrodt Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Mathew George et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8(4), 432-435 (2012-08-18)
Reports describing methadone overdose in adult and pediatric patient populations are not uncommon. Reports in the preterm neonate patient population, however, are infrequent even though the utilization of methadone in that population continues to increase. Significant age-related pharmacokinetic differences complicate
Mei-Han Huang et al.
Toxicology, 280(1-2), 1-9 (2010-11-26)
Methadone (Mtd) is a widely used opioid drug associated with the side effect of hyperprolactinemia. The mechanism of how Mtd induces prolactin secretion remains unclear. The effects of Mtd and its two main metabolites (EDDP: (±)-2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolinium percholarate and EMDP: 2-ethyl-5-methyl-3,3-dipnehyl-1-pyrroline)
Teresa R Gray et al.
Forensic science international, 206(1-3), 98-102 (2010-07-30)
Oral fluid testing is widely used for detecting drug exposure, but data describing methadone and metabolites in oral fluid during pharmacotherapy for opioid-dependence are relatively limited. 414 oral fluid specimens from 16 opioid-dependent pregnant women receiving daily methadone were analyzed
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E-022-1ML | 04061833592373 |