04-539
Anti-MAPKAP-K2 Antibody, clone 7H4.2
clone 7H4.2, Upstate®, from mouse
别名:
MAPK-activated protein kinase 2, MAPKAP kinase 2
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
7H4.2, monoclonal
Application:
IP, WB
Citations:
8
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
7H4.2, monoclonal
species reactivity
human, rat, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... MAPKAPK2(9261)
General description
45 kDa
Immunogen
KLH-conjugated synthetic peptide of the C-terminus of the long form of human MAPKAP-K2.
Application
Suggested dilutions:
Immunoblot Analysis: 1:500
Immunoprecipitation: 1:20
Immunoblot Analysis: 1:500
Immunoprecipitation: 1:20
Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
MAP Kinases
Kinases & Phosphatases
MAP Kinases
Kinases & Phosphatases
Physical form
200 µg (1 mg/mL) of mouse monoclonal IgG in PBS containing 0.1% sodium azide.
Format: Purified
Protein A purified
Preparation Note
2 years at -20°C from date of shipment.
Analysis Note
Routinely evaluated by immunoblot.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
L Xu et al.
Oncogene, 25(21), 2987-2998 (2006-01-13)
Although cell invasion is a necessary early step in cancer metastasis, its regulation is not well understood. We have previously shown, in human prostate cancer, that transforming growth factor beta (TGFbeta)-mediated increases in cell invasion are dependent upon activation of
Isaac A Manke et al.
Molecular cell, 17(1), 37-48 (2005-01-05)
The cellular response to DNA damage is mediated by evolutionarily conserved Ser/Thr kinases, phosphorylation of Cdc25 protein phosphatases, binding to 14-3-3 proteins, and exit from the cell cycle. To investigate DNA damage responses mediated by the p38/stress-activated protein kinase (SAPK)
Ainsley A Culbert et al.
The Journal of biological chemistry, 281(33), 23658-23667 (2006-06-16)
MAPK-activated protein kinase 2 (MAPKAP K2 or MK2) is one of several kinases directly regulated by p38 MAPK. A role for p38 MAPK in the pathology of Alzheimer disease (AD) has previously been suggested. Here, we provide evidence to suggest