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Merck
CN

04-901

抗 NR2A 抗体,克隆 A12W,兔单克隆

culture supernatant, clone A12W, Upstate®

别名:

Anti-EPND, Anti-FESD, Anti-GluN2A, Anti-LKS, Anti-NMDAR2A, Anti-NR2A

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
A12W, monoclonal
Application:
WB
Citations:
24
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

A12W, monoclonal

species reactivity

mouse, rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRIN2A(2903)

General description

Mr 170kDa

Immunogen

带有6His标签的融合蛋白,对应于小鼠NMDA受体2A(NR2A)的氨基酸1265-1464

Application

抗NR2A抗体,克隆A12W是针对NR2A的抗体,用于WB。
研究子类别
神经递质 & 受体
研究类别
神经科学

Biochem/physiol Actions

NR2A

Physical form

0.05% 叠氮化钠中的培养上清液

Preparation Note

自收到之日起,在-20°C条件下可稳定保存1年。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。

Analysis Note

已通过免疫印迹对大鼠脑微粒体制剂(目录号12-144)进行常规评估

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 1



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Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Kiraly, DD; Lemtiri-Chlieh, F; Levine, ES; Mains, RE; Eipper, BA
The Journal of Neuroscience null
Chihiro Nozaki et al.
Nature neuroscience, 14(8), 1017-1022 (2011-07-05)
Zinc is abundant in the central nervous system and regulates pain, but the underlying mechanisms are unknown. In vitro studies have shown that extracellular zinc modulates a plethora of signaling membrane proteins, including NMDA receptors containing the NR2A subunit, which
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's



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货号GTIN
04-90104053252586293