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Merck
CN

05-449

抗-Bin1 抗体,克隆99D

clone 99D, Upstate®, from mouse

别名:

Anti-AMPH2, Anti-AMPHL, Anti-CNM2, Anti-SH3P9

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
99D, monoclonal
Application:
IHC, IP, WB
Citations:
11
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

99D, monoclonal

species reactivity

rat, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... BIN1(274)
mouse ... Bin1(30948)

General description

56kDa

Immunogen

对应于人 Bin1氨基酸 189-398的部分融合蛋白 克隆99D

Application

研究类别
细胞凋亡 & 癌症
研究子类别
BCL2 & 抑制
抗-Bin1抗体(克隆99D)是用于IP、WB、 IH.的抗-Bin1 抗体。

Biochem/physiol Actions

Bin1

Physical form

0.1M Tris-甘氨酸,pH 7.4,含0.05%叠氮化钠
形式:纯化
蛋白G色谱

Preparation Note

在-20°C下保存1年

Analysis Note

通过免疫印迹对C2C12细胞的RIPA裂解液进行了常规评估

Other Notes

替代:MAB4131
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Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Telfer, JF; Urquhart, J; Crouch, DH
Cellular Signalling null
R Wechsler-Reya et al.
Cancer research, 57(15), 3258-3263 (1997-08-01)
BIN1 is a putative tumor suppressor that was identified in a genetic screen for polypeptides that interact with the MYC oncoprotein. Using a set of six monoclonal antibodies, we identified and examined biochemical features and localization of cellular BIN1. Epitope
Maxime Sartori et al.
Acta neuropathologica, 138(4), 631-652 (2019-05-09)
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer's disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice