05-577
抗-PP2A抗体，C 亚基，去甲基化，克隆 4b7
ascites fluid, clone 4b7, Upstate®
别名:
Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4b7, monoclonal
Application:
ICC, IP, WB
Citations:
13
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
4b7, monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PPP2CA(5515)
General description
36kDa
Immunogen
对应于人PP2A，C亚基的氨基酸295-309的肽（C-RGEPHVTRRTPDYFL）
Application
抗PP2A抗体，C亚基，去甲基化，克隆4b7，是一种针对PP2A的抗体，可用于IC、IP & WB。
研究子类别
激酶&磷酸酶
神经退行性疾病
激酶&磷酸酶
神经退行性疾病
研究类别
信号传导
神经科学
信号传导
神经科学
Biochem/physiol Actions
未甲基化的PP2A，C亚基
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
腹水
Preparation Note
在-20°C下可保存2年
Analysis Note
对照
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。 加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
阳性抗原对照：货号12-301，未刺激的A431细胞裂解液。 加入2.5µL 2-巯基乙醇/100µL裂解液，煮沸5分钟以减少制备量。在微凝胶每个泳道上样20µg经还原的裂解液。
已通过免疫印迹法对A431细胞的RIPA裂解液进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
10 - Combustible liquids
wgk
WGK 1
X X Yu et al.
Molecular biology of the cell, 12(1), 185-199 (2001-02-13)
Binding of different regulatory subunits and methylation of the catalytic (C) subunit carboxy-terminal leucine 309 are two important mechanisms by which protein phosphatase 2A (PP2A) can be regulated. In this study, both genetic and biochemical approaches were used to investigate
C S Moreno et al.
The Journal of biological chemistry, 275(8), 5257-5263 (2000-02-22)
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many cellular processes including development, neuronal signaling, cell cycle regulation, and viral transformation. PP2A has been implicated in Ca(2+)-dependent signaling pathways, but how PP2A is targeted to
Yunsheng Liu et al.
Neural plasticity, 2019, 4168472-4168472 (2019-03-25)
Exposure to chronic psychiatric stress has been linked to Alzheimer's disease-related tau hyperphosphorylation and abnormalities in glutamate neurotransmission. However, the pathological relationship between glutamatergic dysfunction and tau phosphorylation in the cerebral cortex under chronic psychiatric stress is not fully understood.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 05-577 | 04053252339370 |