05-726
抗-53BP1抗体，克隆BP13
clone BP13, Upstate®, from mouse
别名:
Anti-53BP1, Anti-p202, Anti-p53BP1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
BP13, monoclonal
Application:
ICC, IP, WB
Citations:
12
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
BP13, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TP53BP1(7158)
General description
~250kDa
Immunogen
分别对应于人53BP1残基1-337、338-671和11331-1664的三个GST融合蛋白的混合物
Application
不会与小鼠发生交叉反应。
使用抗53BP1抗体（克隆BP13，小鼠单克隆抗体）检测 53BP1，该抗体已被证明可在 IP、WB、ICC 中发挥作用。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
53BP1
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
蛋白G纯化
Preparation Note
在-20°C下可保存2年
Analysis Note
通过免疫印迹对HeLa细胞的裂解液进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
Quantitative analysis of DNA-damage response factors after sequential ion microirradiation.
Christoph Greubel, Volker Hable, Guido A Drexler, Andreas Hauptner, Steffen Dietzel et al.
Radiation and Environmental Biophysics null
I M Ward et al.
The Journal of biological chemistry, 276(51), 47759-47762 (2001-10-24)
H2AX, a member of the histone H2A family, is rapidly phosphorylated in response to ionizing radiation. This phosphorylation, at an evolutionary conserved C-terminal phosphatidylinositol 3-OH-kinase-related kinase (PI3KK) motif, is thought to be critical for recognition and repair of DNA double
Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile.
Fay Minty, Johanna K Thurlow, Paul R Harrison, E Kenneth Parkinson
Experimental Cell Research null