05-747
抗磷酸化MEK1（Ser218/222）/MEK2（Ser222/226）抗体（兔单克隆）
Upstate®, from rabbit
别名:
Anti-CFC3, Anti-MAPKK1, Anti-MEK1, Anti-MEL, Anti-MKK1, Anti-PRKMK1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
human, mouse, rat
Application:
WB
Citations:
11
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pSer218/pSer222)
Gene Information
human ... MAP2K1(5604)
General description
45kDa
Immunogen
含DpSMANpSF的肽，其中pS对应于人MEK1磷酸化氨基酸 218 和 222。
Application
使用经验证可用于WB的该抗磷酸化MEK1（Ser218/222）/MEK2（Ser222/226） 抗体来检测磷酸化MEK1（Ser218/222）/MEK2（Ser222/226） 。
研究子类别
MAP激酶
MAP激酶
研究类别
信号传导
信号传导
Biochem/physiol Actions
磷酸化MEK1/MEK2
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
纯化蛋白A
Preparation Note
在-20°C下可保存2年
Analysis Note
通过免疫印迹对 B-Raf处理的PC-12细胞的 RIPA裂解液进行了常规评估
Other Notes
替代：04-1017
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1.
Gopalbhai, Kailesh, et al.
The Journal of Biological Chemistry, 278, 8118-8125 (2003)
J C S Ho et al.
Oncogene, 35(7), 897-907 (2015-06-02)
HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) kills tumor cells broadly suggesting that conserved survival pathways are perturbed. We now identify nucleotide-binding proteins as HAMLET binding partners, accounting for about 35% of all HAMLET targets in a protein microarray
C Hodge et al.
The Journal of biological chemistry, 273(47), 31327-31336 (1998-11-13)
Growth hormone (GH), a major regulator of normal body growth and metabolism, regulates cellular gene expression. The transcription factors Elk-1 and Serum Response Factor are necessary for GH-stimulated transcription of c-fos through the Serum Response Element (SRE). GH stimulates the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 05-747 | 04053252370472 |