biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat, mouse
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PHB2(11331)
General description
37kDa
Immunogen
His6-tagged fusion protein corresponding to amino acid residues 88-299 of mouse REA-1/BAP-37/prohibitin-related protein
Application
Detect REA with Anti-REA Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Biochem/physiol Actions
REA
Physical form
200 μg of protein A purified rabbit IgG in 200 μL of 0.07 M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol.
Format: Purified
Protein A chromatography
Preparation Note
2 years at -20°C
Analysis Note
Control
3T3 nuclear extract
3T3 nuclear extract
routinely evaluated by immunoblot on 3T3 nuclear extract
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation.
Y Zhang,Y Wang,Y Xiang,W Lee
Journal of Thrombosis and Haemostasis null
Sonia Núñez-Vázquez et al.
Oncogenesis, 10(9), 64-64 (2021-09-29)
Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was described that
Sonia Núñez-Vázquez et al.
The FEBS journal, 288(4), 1271-1285 (2020-07-11)
Fluorizoline is a new synthetic molecule that induces p53-independent apoptosis, in several tumor cell lines and in primary leukemia cells, by selectively targeting prohibitins (PHBs). In this study, we describe how fluorizoline induces BCL-2 homology 3-only protein NOXA, without modulating
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 07-234 | 04053252322594 |