产品名称
抗-Raf-1抗体, Upstate®, from rabbit
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... RAF1(5894)
General description
70kDa
Immunogen
对应于人 Raf-1 氨基酸 637-648 的肽。
Application
抗-Raf-1 抗体可检测Raf-1 水平 & 已发布 & 经过验证可用于IP & WB。
研究子类别
MAP激酶
MAP激酶
研究类别
信号传导
信号传导
Biochem/physiol Actions
Raf-1
Physical form
0.1M Tris-甘氨酸（pH 7.4），0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
纯化蛋白A
Preparation Note
-20degC下保存2年
Analysis Note
对照
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
已通过免疫印迹法对3T3/A31细胞的RIPA裂解液进行了常规评估
Other Notes
替代：04-412
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk.
Sonja I Gringhuis,Jeroen den Dunnen,Manja Litjens,Michiel van der Vlist,Brigitte Wevers et al.
Nature Immunology null
L Lin et al.
Cell death and differentiation, 13(11), 1982-1993 (2006-04-01)
Melanoma differentiation-associated gene-5 (mda-5) was the first molecule identified in nature whose encoded protein embodied the unique structural combination of an N-terminal caspase recruitment domain and a C-terminal DExD/H RNA helicase domain. As suggested by its structure, cumulative evidences documented
Kiril Bidzhekov et al.
Journal of cellular and molecular medicine, 11(6), 1395-1407 (2008-01-22)
Mouse embryonic endothelial progenitor cells (eEPCs) acquire a mature phenotype after treatment with cyclic adenosine monophosphate (cAMP), suggesting an involvement of Raf serine/threonine kinases in the differentiation process. To test this idea, we investigated the role of B-Raf and C-Raf
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 07-396 | 04053252679001 |