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Merck
CN

07-667

Anti-Amyloid Precursor Protein (APP) Antibody

UPSTATE®, rabbit polyclonal

别名:

Anti-AAA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-alpha-sAPP, Anti-preA4

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
IP, WB
Citations:
11
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产品名称

抗APP抗体, Upstate®, from rabbit

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

species reactivity (predicted by homology)

chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... APP(351)

General description

110kDa

Immunogen

与人淀粉样前体蛋白(APP)的44-61位氨基酸对应的合成肽

Application

研究类别
神经科学
抗APP抗体可检测APP水平&,已发表 &并经过验证可用于IP &WB。
研究子类别
泛素 & 泛素代谢

神经退行性疾病

Biochem/physiol Actions

APP

Physical form

免疫亲和纯化
纯化的兔多克隆抗体,溶于含有0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。

Preparation Note

自收到之日起,在2-8°C条件下可稳定保存1年。

Analysis Note

已通过免疫印迹进行常规评估。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 1



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Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein.
Puglielli, Luigi, et al.
Journal of Molecular Neuroscience, 24, 93-96 (2004)
Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Wilson, Christina A, et al.
Journal of Neuroscience Research, 74, 361-369 (2003)
Structure and function of amyloid in Alzheimer's disease.
Morgan, Carlos, et al.
Progress in Neurobiology, 74, 323-349 (2004)



全球贸易项目编号

货号GTIN
07-66704053252275562