biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr172)
Gene Information
human ... PRKAA1(5562)
General description
Mr 63 kDa
Immunogen
KLH偶联的合成肽，对应于人AMP活化蛋白激酶α2（AMPKα2）的磷酸化Thr172周围的氨基酸。
Application
抗磷酸化AMPK α（Tyr342）抗体是针对磷酸化AMPKα（Tyr342）的抗体，可用于WB。
Biochem/physiol Actions
可识别磷酸化AMPKα。
Physical form
形式：纯化
Analysis Note
对照
血清饥饿HEK293 细胞
血清饥饿HEK293 细胞
已通过免疫印迹对过夜饥饿的HEK293 细胞和部分纯化的大鼠肝脏AMPK的RIPA裂解液进行了常规评估
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Mathias Fasshauer et al.
Biochimie, 86(11), 779-784 (2004-12-14)
Several adipocyte-secreted factors have been demonstrated to potentially link obesity, insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin-sensitizing and anti-inflammatory adipokine, concentrations of which are decreased in obesity-associated metabolic and vascular disorders. Recently, two adiponectin receptors (AdipoR)
Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.
Rutter, Guy A, et al.
The Biochemical Journal, 375, 1-16 (2003)
J F P Wojtaszewski et al.
Biochemical Society transactions, 31(Pt 6), 1290-1294 (2003-12-04)
The AMPK (5'AMP-activated protein kinase) is becoming recognized as a critical regulator of energy metabolism. However, many of these effects in muscle metabolism have been ascribed to AMPK based on the use of the unspecific activator AICAR (5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside). Using mouse