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09-217

Anti-Raptor Antibody

Name: Anti-Raptor Antibody
Brand: MM

Upstate^®, from rabbit

别名:

p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IP, WB

Citations:

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属性

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate^®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

NM_020761.2

UniProt accession no.

Q8N122

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... RPTOR(57521)

说明

General description

150 kDa

Immunogen

KLH conjugated peptide encompassing the N-terminal region of human Raptor.

Application

Detect Raptor using this anti-Raptor Antibody validated for use in IP & WB.

Research Category
Signaling

Research Sub Category
PI3K, Akt, & mTOR Signaling

Biochem/physiol Actions

Other species have not been tested.

Physical form

Affinity purified rabbit polyclonal IgG in 0.02M PBS, 0.25M sodium chloride containing 0.1% sodium azide and 50% glycerol.

ImmunoAffinity Purified

Preparation Note

2 years at -20°C from date of shipment

Analysis Note

Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.

Bruno D Fonseca et al.

The Journal of biological chemistry, 286(31), 27111-27122 (2011-06-11)

The mammalian target of rapamycin complex 1 (mTORC1) links the control of mRNA translation, cell growth, and metabolism to diverse stimuli. Inappropriate activation of mTORC1 can lead to cancer. Phorbol esters are naturally occurring products that act as potent tumor

null

Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise.

William Apró et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(10), 4358-4373 (2015-07-15)

We examined how the stimulatory effect of leucine on the mechanistic target of rapamycin complex 1 (mTORC1) pathway is affected by the presence of the remaining essential amino acids (EAAs). Nine male subjects performed resistance exercise on 4 occasions and

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货号	GTIN
09-217	04053252405389