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1.00160

硼酸

Name: 硼酸
Brand: MM

crystalline, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF, ChP

别名:

Orthoboric acid, Trihydroxidoboron

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关于此项目

线性分子式:

H₃BO₃

化学文摘社编号:

10043-35-3

分子量:

61.83

UNSPSC Code:

12352301

EC Index Number:

233-139-2

MDL number:

MFCD00011337

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属性

agency

ChP, JP, NF, Ph. Eur., BP

Quality Level

500

vapor pressure

2.6 mmHg ( 20 °C)

product line

EMPROVE^® ESSENTIAL

assay

99.5-100.5% dry basis (alkalimetric)

form

crystalline, solid

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

pH

3.8-4.8 (20 °C, 33 g/L in H₂O)

mp

160 °C (dec.) (lit.)

solubility

49.2 g/L

density

1.489 g/cm³ at 23 °C

anion traces

sulfate (SO₄^2-): ≤0.04%

cation traces

As: ≤0.0001%, heavy metals (as Pb): ≤0.0015%

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

SMILES string

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

说明

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Boric acid has antimicrobial characteristics and is therefore typically used as preservative in pharmaceutical formulations and cosmetics. It is also used as buffering agent and pH adjuster.

Preparation Note

Must be subjected to further processing during the preparation of injectable dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS08

signalword

Danger

hcodes

H360FD

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

flash_point_f

Not applicable

flash_point_c