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线性分子式:
NH2CH2COOH
化学文摘社编号:
分子量:
75.07
EC Index Number:
200-272-2
UNSPSC Code:
12352121
Beilstein/REAXYS Number:
635782
MDL number:
Quality Level
agency
BP, ChP, JP, Ph. Eur., USP
vapor pressure
0.0000171 Pa ( 25 °C)
description
EMPROVE® EXPERT Ph Eur,BP,JP,USP
product line
EMPROVE® EXPERT
assay
98.5-101.0% (calculated on dried substance, perchloric acid titration)
form
crystalline, solid
technique(s)
inhibition assay: suitable
pH
5.9-6.4 (20 °C, 50 g/L in H2O)
pKa (25 °C)
(1) 2.35, (2) 9.60, 2.35
mp
240 °C (dec.) (lit.)
solubility
soluble 250 g/L
density
1.161 g/cm3 at 20 °C
application(s)
liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
storage temp.
2-30°C
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
General description
Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Glycine is an amino acid which is used widely in the biopharma industry as stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine cryst. Emprove® Expert is especially suitable for high-risk applications.
Due to its low microbial and endotoxin limits, Glycine cryst. Emprove® Expert is especially suitable for high-risk applications.
Biochem/physiol Actions
脊髓中的抑制性神经递质,NMDA受体的变构调节器。
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
The substance 1.00590 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.
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存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
商品
This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1005905000 | 04027269222758 |
| 1005909050 | 04027269222772 |
| 1005900001 | 04027269300494 |
| 1005901000 | 04027269222741 |
| 1005909012 | 04027269260668 |
| 1005909025 | 04027269222765 |
| 1005909026 | 04027269237578 |