1.00681
琥珀酸
crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE
别名:
丁二酸
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线性分子式:
HOOCCH2CH2COOH
化学文摘社编号:
分子量:
118.09
EC Index Number:
203-740-4
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
1754069
MDL number:
grade
ACS reagent
Quality Level
agency
ChP, JPE, NF
product line
EMPROVE® ESSENTIAL
assay
99.0-100.5% (HPLC)
form
crystalline, solid
autoignition temp.
470 °C
technique(s)
API processing | cocrystal formation: suitable, API processing | salt formation: suitable
bp
235 °C (lit.), 235 °C/1013 hPa
mp
184-186 °C (lit.)
transition temp
flash point 206 °C
solubility
58 g/L
density
1.56 g/cm3 at 20 °C
anion traces
chloride (Cl-): ≤0.001%, phosphate (PO43-): ≤0.001%, sulfate (SO42-): ≤0.003%
cation traces
As: ≤0.0002%, Fe: ≤5 ppm, heavy metals (as Pb): ≤0.0020%, heavy metals (as Pb): ≤5 ppm
application(s)
liquid formulation
pharma/biopharma processes
pharmaceutical
solid formulation
storage temp.
2-30°C
SMILES string
OC(=O)CCC(O)=O
InChI
1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChI key
KDYFGRWQOYBRFD-UHFFFAOYSA-N
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Succinic acid is a commonly used ingredient in pharmaceutical applications. In such applications it has been used primarily for solid oral dosage forms.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1006815000 | 04022536008943 |
| 1006819050 | 04022536008950 |