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1079

N-Acetyl-D-glucosamine

Name: N-Acetyl-D-glucosamine
Brand: MM

An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (Ki = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

别名:

N-Acetyl-D-glucosamine, NAG, GlcNAc

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关于此项目

经验公式（希尔记法）:

C₈H₁₅NO₆

化学文摘社编号:

7512-17-6

分子量:

221.21

UNSPSC Code:

12352201

NACRES:

NA.21

MDL number:

MFCD00061615

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属性

Quality Level

100

assay

≥98% (HPLC)

form

powder

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

off-white to beige, white to off-white

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

N(C1C(OC(C(C1O)O)CO)O)C(=O)C

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)

InChI key

OVRNDRQMDRJTHS-UHFFFAOYSA-N

说明

General description

Acceptor substrate for galactosyltransferases. Lectin inhibitory amino sugar. When added to the medium, it improves the recovery of Haemophilus influenza from sputum. A competitive inhibitor of β-N-acetylhexosaminidase (K_i = 430 µM).

An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (K_i = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Sakai, K., et al. 1994. Appl. Environ. Microbiol. 60, 2911.
Moller, L.V., et al. 1993. J. Clin. Microbiol. 31, 1952.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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N-acetyl-D-glucosamine medium improves recovery of Haemophilus influenzae from sputa of patients with cystic fibrosis.

L V Möller et al.

Journal of clinical microbiology, 31(7), 1952-1954 (1993-07-01)

A modified selective medium supplemented with N-acetyl-D-glucosamine (NAG), hemin, and NAD plus two cefsulodin disks, for primary isolation of nonencapsulated Haemophilus influenzae from sputum of patients with cystic fibrosis, is described. Isolation of H. influenzae from this medium, designated NAG

Purification and characterization of thermostable beta-N-acetylhexosaminidase of Bacillus stearothermophilus CH-4 isolated from chitin-containing compost.

K Sakai et al.

Applied and environmental microbiology, 60(8), 2911-2915 (1994-08-01)

Thermostable exochitinase was purified to homogeneity from the culture fluid of Bacillus stearothermophilus CH-4, which was isolated from agricultural compost containing shrimp and crabs. The enzyme was a single polypeptide with a molecular mass of 74 kDa, and the N-terminal

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