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Merck
CN

12667-M

Human Serum Albumin

30% Aqueous Solution

别名:

Albumin, Human Serum, 30% Aqueous Solution

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化学文摘社编号:
UNSPSC Code:
12352202
MDL number:
NACRES:
NA.25
Biological source:
human
Assay:
≥95% (agarose gel electrophoresis)
Form:
liquid
Technique(s):
cell culture | mammalian: suitable
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产品名称

Albumin, Human Serum, 30% Aqueous Solution,

biological source

human

Quality Level

description

Merck USA index - 14, 8468

assay

≥95% (agarose gel electrophoresis)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

General description

Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein, which is abundantly found in the plasma. It contains three homologous domains, numbered I, II, and III. Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.

Biochem/physiol Actions

Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids. It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals. HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis. It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis. HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.

Physical form

30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)


存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

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Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity



全球贸易项目编号

货号GTIN
12667-50ML-M04055977222081