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1.37028

甘油

greener alternative

anhydrous (vegetable), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS

别名:

1,2,3-丙三醇, 甘油

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关于此项目

线性分子式:
HOCH2CH(OH)CH2OH
化学文摘社编号:
56-81-5
分子量:
92.09
EC Index Number:
200-289-5
UNSPSC Code:
12352104
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722
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grade

ACS reagent

Quality Level

500

agency

BP, ChP, JP, Ph. Eur., USP

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

EMPROVE® EXPERT

assay

≤98.0-101.0% (calculated on anhydrous substance, alkalimetric), ≥99.5% (calculated on anhydrous substance, GC)

form

liquid

autoignition temp.

698 °F

expl. lim.

2.6-11.3 % (v/v)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

electrophoresis: suitable

refractive index

n20/D 1.474 (lit.)

pH

5 (20 °C, 100 g/L in H2O)

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

transition temp

flash point 199 °C

density

1.25 g/mL (lit.)

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical

greener alternative category

Aligned,

storage temp.

2-25°C

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

General description

在制剂配制过程中，寻找既能满足您的应用需求同时又符合监管要求的合适辅料是一项复杂棘手的难题。凭借应用专业技术和监管专业知识，我们可针对您的开发、扩大化及生产过程提供提供支持。
作为Emprove®计划的一部分，我们的原料随附完备的支持文件，以帮助您确保自己的制药和生物制药产品合规、维持完整供应链透明度并规避相关风险。我们的SAFC®高质量产品线面向生物制药和制药制剂和生产应用，经过严格的质控程序检验，同时严格遵守适用的cGMP指南生产。
我们致力于为您提供符合一项或多项“绿色化学 12 项原则”的绿色替代产品。本品是一种生物基甘油，符合绿色化学第5项“更安全的溶剂和助剂”原则和第7项“使用可再生原料”原则。点击此处 以获取更多信息。

Application

甘油可用于各种固体、半固体和液体配方，包括眼科、口服固体和口服液剂量、片剂包衣、乳霜和凝胶等。它适用于保湿剂、润肤剂、溶剂/助溶剂、增粘剂和增塑剂等。
无水甘油（果蔬）Emprove® Expert内毒素和生物负荷低，是高风险应用的不二之选。

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

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