14-155
组蛋白H1蛋白，20 mg
Purified bovine Histone H1 protein for use as a substrate in histone modification assays (HAT, HDAC, DNMT) and chromatin assembly studies.
别名:
Linker Histone H1
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
bovine
Mol wt:
Mw 32 kDa
biological source
bovine
Quality Level
mol wt
Mw 32 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
H1和相关的接头组蛋白对于维持高级染色质结构和调节基因表达都很重要。通过组蛋白H1与核小体二元组和进入和离开核心颗粒的接头DNA的结合来提供核小体稳定作用。其他实验证据说明了组蛋白H1对染色质排列和紧实的影响。组蛋白H1蛋白家族包含五个体细胞变体（H1.1，H1.2，H1.3，H1.4和H1.5），它们在几乎所有细胞类型中表达。
产品来源：小牛胸腺富含赖氨酸部分
Physical form
通过0.2微米膜过滤器灭菌
Preparation Note
在-20°C下保存1年
Analysis Note
使用cdk2/细胞周期蛋白A（活性（14-448）磷酸化组蛋白H1）通过激酶测定法进行常规评估。
Other Notes
比活相关数据，请参阅检验报告以获取该酶的单独批次。
该产品来自牛源。该产品向某些国家的出口可能受到限制。请联系客户服务或您的当地经销商询问产品的供应和出口选项。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Hyo Kyun Chung et al.
The Journal of biological chemistry, 278(30), 28079-28088 (2003-04-30)
The Gadd45 family of proteins includes Gadd45alpha, MyD118/Gadd45beta, and CR6/OIG37/Gadd45gamma. These proteins play important roles in maintaining genomic stability and in regulating the cell cycle. This study reports the cloning of a novel protein called CR6-interacting factor 1 (CRIF1) which
Sabrina Absalon et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14645-14659 (2013-09-13)
MicroRNA (miRNA) functions in the pathogenesis of major neurodegenerative diseases such as Alzheimer's disease (AD) are only beginning to emerge. We have observed significantly elevated levels of a specific miRNA, miR-26b, in the defined pathological areas of human postmortem brains
Mihkel Örd et al.
Cell reports, 31(11), 107757-107757 (2020-06-20)
The hydrophobic patch (hp), a docking pocket on cyclins of CDKs (cyclin-dependent kinases), has been thought to accommodate a single short linear motif (SLiM), the "RxL or Cy" docking motif. Here we show that hp can bind different motifs with
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 14-155 | 04053252362125 |