description
Bafilomycin A1 is a specific potent inhibitor of vacuolar-type H+-ATPases, and blocks lysosomal cholesterol transport in macrophages.
Quality Level
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
storage temp.
−20°C
Application
巴佛洛霉素A1已被用于：
- 作为自噬抑制剂用于研究其对大鼠脑创伤（TBI）引起的细胞死亡和损伤的作用
- 用于 pH luorin 测定中神经元的处理以测定突触活动中的内噬作用
- 阻止小鼠胚胎成纤维细胞中的自噬
Biochem/physiol Actions
抑制剂种类：激酶
Physical form
C35H58O9
Preparation Note
在-20°C下可保存3年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
涉药品监管产品
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