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Merck
CN

309825

Dihydrorhodamine 123

Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite.

别名:

Dihydrorhodamine 123

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关于此项目

经验公式(希尔记法):
C21H18N2O3
化学文摘社编号:
分子量:
346.38
UNSPSC Code:
12352116
NACRES:
NA.21
MDL number:
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Quality Level

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

pink-white

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

Nc1cc2c(cc1)C(c4c(cc(cc4)N)O2)c3c(cccc3)C(=O)OC

InChI

1S/C21H18N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,20H,22-23H2,1H3

InChI key

FNEZBBILNYNQGC-UHFFFAOYSA-N

General description

Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite. Dihydrorhodamine is not fluorescent unless it is converted to rhodamine 123.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Detection of reactive oxygen species (ROS)
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Crow, J.P. 1997. Nitric Oxide1, 145.
Kim, Y.M., et al. 1996. Infect Immun. 64, 3074.
Williams, M.S., and Henkart, P.A. 1996. J. Immunol. 157, 2395.
van de Water, B., et al. 1995. Mol. Pharmacol. 48, 928.
Royall, J.A., and Ischiropoulos, H. 1993. Arch. Biochem. Biophys. 302, 348.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
309825-5MG04055977216813