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407286

Anti-Integrin α_v (Ab-1) Mouse mAb (272-17E6)

Name: Anti-Integrin α<sub>v</sub> (Ab-1) Mouse mAb (272-17E6)
Brand: MM

liquid, clone 272-17E6, Calbiochem^®

别名:

Anti-CD51

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

272-17E6, monoclonal

Species reactivity:

human

Application:

—

Citations:

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属性

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

272-17E6, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Cell Inhibition Assays
ELISA
Flow Cytometry (2.5 µg/mL)
Immunoprecipitation (2.5 µg/mL))

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGAV(3685)

说明

General description

Purified mouse monoclonal antibody. Recognizes the α_v integrin chain and all α_v-containing integrins.

Recognizes the α_v integrin chain and all α_v-containing integrins.

This Anti-Integrin α_v (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin α_v (Ab-1).

Immunogen

Human

human placental α_vβ₃ integrin

Application

Cell Inhibition Assays (see application reference)

ELISA (see application reference)

Flow Cytometry (2.5 µg/ml, see application reference)

Immunoprecipitation (2.5 µg/ml, see application reference)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, pH 7.6.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Akiyama, S.K. 1996. Hum. Cell9, 181.
Hynes, R.O. 1992. Cell69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell45, 549.

Cross-reacts with all α_v integrins. Blocks cell adhesion mediated by all α_v integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Quantifying amyloid beta (AI?)-mediated changes in neuronal morphology in primary cultures: implications for phenotypic screening.

Nguyen, et al.

Journal of Biomolecular Screening, 17, 835-842 (2012)

Dentin matrix protein 1 enhances invasion potential of colon cancer cells by bridging matrix metalloproteinase-9 to integrins and CD44.

Abdullah Karadag et al.

Cancer research, 65(24), 11545-11552 (2005-12-17)

The up-regulation of various matrix metalloproteinases (MMP), certain cell receptors such as integrins and CD44, and the SIBLING family of integrin-binding glycophosphoproteins have been reported separately and in various combinations for many types of tumors. The mechanisms by which these

全球贸易项目编号

货号	GTIN
407286-100UG	04055977188776