422709
KN-92
KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM Kinase II inhibitor.
别名:
KN-92, 2-[N-(4-Methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, Phosphate
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关于此项目
经验公式（希尔记法）:
C24H25ClN2O3S · xH3PO4
化学文摘社编号:
分子量:
456.98
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32
Assay:
≥95% (HPLC)
Form:
viscous liquid
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
Quality Level
assay
≥95% (HPLC)
form
viscous liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[P](=O)(O)(O)O.[S](=O)(=O)(Nc2c(cccc2)CN(C\C=C\c3ccc(cc3)Cl)C)c1ccc(cc1)OC
InChI
1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;
InChI key
XRQHWVVDNMJDEQ-IPZCTEOASA-N
General description
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM kinase II inhibitor
Useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM kinase II inhibitor
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 4 months at -20°C.
Other Notes
Fan, G.H., et al. 1999. Mol. Pharmacol.56, 39.
Fan, G.H., et al. 1997. Neuropharmacology 36, 1763.
Fan, G.H., et al. 1997. Neuropharmacology 36, 1763.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Estelle R Simo-Cheyou et al.
Journal of cellular physiology, 232(12), 3496-3509 (2017-01-21)
An upregulation of Egr-1 expression has been reported in models of atherosclerosis and intimal hyperplasia and, various vasoactive peptides and growth promoting stimuli have been shown to induce the expression of Egr-1 in vascular smooth muscle cells (VSMC). Angiotensin-II (Ang-II)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 422709-1MG | 07790788050177 |