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481001

Anti-Neutrophil Elastase Rabbit pAb

Name: Anti-Neutrophil Elastase Rabbit pAb
Brand: MM

liquid, Calbiochem^®

别名:

Neutrophil elastase antibody, Rabbit monoclonal antibody

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

human

Application:

—

Citations:

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属性

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:1000)
Immunoblotting
Immunoelectrophoresis
Immunoprecipitation )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ELANE(1991)

说明

General description

Ammonium sulfate precipitated rabbit polyclonal antibody. Recognizes human neutrophil elastase.

Recognizes the neutrophil elastase protein.

This Anti-Neutrophil Elastase Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunoelectrophoresis, Immunoprecipitation for the detection of Neutrophil Elastase.

Immunogen

Human

human neutrophil elastase

Application

ELISA (≥ 1:1000)

Immunoblotting (see comments)

Immunoelectrophoresis (see comments)

Immunoprecipitation (see comments)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, pH 7.5.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Single arc by immunoelectrophoresis against neutrophil granule extract and human neutrophil elastase. This antibody has also been reported to work for immunoblotting and immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Diverse stimuli engage different neutrophil extracellular trap pathways.

Elaine F Kenny et al.

eLife, 6 (2017-06-03)

Neutrophils release neutrophil extracellular traps (NETs) which ensnare pathogens and have pathogenic functions in diverse diseases. We examined the NETosis pathways induced by five stimuli; PMA, the calcium ionophore A23187, nigericin, Candida albicans and Group B Streptococcus. We studied NET

Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes.

Jiram Torres-Ruiz et al.

Frontiers in immunology, 12, 689966-689966 (2021-09-28)

Most of the explanatory and prognostic models of COVID-19 lack of a comprehensive assessment of the wide COVID-19 spectrum of abnormalities. The aim of this study was to unveil novel biological features to explain COVID-19 severity and prognosis (death and

Release of cystic fibrosis airway inflammatory markers from Pseudomonas aeruginosa-stimulated human neutrophils involves NADPH oxidase-dependent extracellular DNA trap formation.

Dae-goon Yoo et al.

Journal of immunology (Baltimore, Md. : 1950), 192(10), 4728-4738 (2014-04-18)

Cystic fibrosis (CF) airways are characterized by bacterial infections, excess mucus production, and robust neutrophil recruitment. The main CF airway pathogen is Pseudomonas aeruginosa. Neutrophils are not capable of clearing the infection. Neutrophil primary granule components, myeloperoxidase (MPO) and human

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货号	GTIN
481001-1ML	07790788056353