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48-681MAG

MILLIPLEX® Multi-Pathway Signaling Panel

Premixed Multi-Pathway Total 9-Plex Cell Signaling Panel

别名:

Luminex® Cell Signaling Assay, Millipore Cell Signaling Assay, Signal Transduction Panel, MAPK STAT TCR assay, multi-pathway signaling panel, multi-target phosphorylation panel, phosphoprotein multiplex assay, rat cell signaling panel, rat intracellular signaling biomarkers

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NACRES:
NA.47
UNSPSC Code:
12161503
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产品名称

MILLIPLEX® Multi-Pathway Signaling Panel, Premixed Multi-Pathway Total 9-Plex Cell Signaling Panel

Quality Level

200

species reactivity

human, mouse, rat

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel includes total proteins from multiple signaling pathways that regulate cell survival, proliferation, inflammation, and transcriptional activity. ERK1/2, JNK, and p38 are core components of the MAPK pathway involved in stress and growth responses. Akt regulates cell survival and metabolism. NFκB controls inflammatory and immune signaling. STAT3 and STAT5A/B mediate cytokine-driven transcriptional regulation. CREB is a transcription factor activated by cAMP signaling, and p70 S6 Kinase plays a role in protein synthesis and cell growth. Quantifying these total proteins supports pathway profiling and comparative analysis across experimental conditions.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 9 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: ERK/MAPK 1/2, Akt, STAT3, JNK, p70 S6 Kinase, NFκB, STAT5A/B, CREB, p38

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).

Features and Benefits

  • Simultaneously detect 9 total proteins across key signaling pathways
  • Covers MAPK, STAT, Akt, NFκB, and CREB pathways for broad cellular profiling
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from diverse experimental conditions
  • Ideal for signal transduction, oncology, immunology, and toxicology research
  • Fast, convenient alternative to Western blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

存储类别

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

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