产品名称
Prostaglandin E2, Involved in vasodilator actions of kinins such as bradykinin.
Quality Level
description
Merck USA index - 14, 7877
assay
>98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to light yellow
solubility
acetone: soluble, ethanol: soluble, ethyl acetate: soluble, methanol: soluble
shipped in
wet ice
storage temp.
−20°C
SMILES string
OC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC
InChI
1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+
InChI key
XEYBRNLFEZDVAW-RTYMFESYSA-N
General description
Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells
Other Notes
Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 538904-1MG | 07790788051266 |

