573102
S3I-201
≥95% (HPLC), solid, STAT3 inhibitor, Calbiochem®
别名:
STAT3抑制剂VI，S3I-201
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关于此项目
经验公式（希尔记法）:
C16H15NO7S
化学文摘社编号:
分子量:
365.36
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
STAT3抑制剂VI，S3I-201, STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
light beige
solubility
DMSO: 10 mg/mL (Use only fresh, anhydrous DMSO.)
shipped in
ambient
storage temp.
−20°C
SMILES string
[S](=O)(=O)(OCC(=O)Nc2cc(c(cc2)C(=O)O)O)c1ccc(cc1)C
InChI
1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
InChI key
HWNUSGNZBAISFM-UHFFFAOYSA-N
General description
一种细胞渗透性氨基水杨酸化合物，可结合Stat3-SH2结构域并阻止Stat3磷酸化/激活、二聚化、DNA结合和Stat3依赖性转录。显示在体外培养（有效浓度≤100 µM）和体内鼠异种移植模型（5 mg/kg，i.v.）中抑制Stat3依赖性肿瘤生长。也可以50 mM的DMSO溶液（目录号573130）提供。
Packaging
用惰性气体包装
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：监管审查（Z）
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 573102-10MG | 04055977266429 |
| 573102-25MG | 04055977266436 |