574625
Suramin sodium salt
≥98% (HPLC), crystalline solid, P2Y antagonist, Calbiochem®
别名:
苏拉明，钠盐, P2Y拮抗剂 I，嘌呤能受体P2Y拮抗剂I，PTP抑制剂VI
选择尺寸
关于此项目
产品名称
苏拉明，钠盐, A reversible and competitive inhibitor of protein tyrosine phosphatases.
Quality Level
description
Merck USA index - 14, 9006
assay
≥98% (HPLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[S](=O)(=O)([O-])c1cc2c(c(c1)[S](=O)(=O)O)c(ccc2[S](=O)(=O)O)\N=C(/[O-])\c3cc(c(cc3)C)\N=C(/[O-])\c4cc(ccc4)\N=C(\Nc5cc(ccc5)\C(=N\c6c(ccc(c6)\C(=N\c7c8c(c(cc7)[S](=O)(=O)O)cc(cc8[S](=O)(=O)O)[S](=O)(=O)O)\[O-])C)\[O-])
InChI
1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6
InChI key
VAPNKLKDKUDFHK-UHFFFAOYSA-H
General description
Biochem/physiol Actions
蛋白质酪氨酸磷酸酶
Preparation Note
Other Notes
Hohenegger, M., et al. 1998.Proc.Natl.Acad.Sci. USA 95, 346.
Waldhoer, M., et al. 1998.Mol.Pharmacol.53, 808.
Zhang, Y.L., et al. 1998.J. Biol. Chem. 273, 12281.
Hohenegger, M., et al. 1996.Mol.Pharmacol.50, 1443.
Emmick, J.J., et al. 1994.J. Pharmacol.Exp.Ther.269, 717.
Denhertog, A., et al. 1992.J. Physiol.454, 591.
Nakajima, M., et al. 1991.J. Biol. Chem.266, 9661.
Wilks, J.W., et al. 1991.Int. J. Radiat.Biol.60, 73.
Huang, R.C., et al. 1990.Mol.Pharmacol.37, 304.
Kopp, R. and Pfeiffer, A. 1990.Cancer Res.50, 6490.
Legal Information
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
"The SIRTainty™ Class III HDAC Assay utilizes a novel patent pending technology for the sensitive detection of all known sirtuin family members. Unlike conventional assays that are dependent upon a single pre-labeled fluorescently tagged substrate, the SIRTainty Class III HDAC Assay employs untagged acetylated peptide substrates. This approach not only enables unparalleled flexibility in your choice of sirtuin isoform and peptide substrate, but also eliminates the potential for artifacts due to the use of artificial substrates containing bulky fluorophores."
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 574625-50MG | 04055977189636 |