662141
PR-619
≥99% (HPLC), solid, DUB inhibitor, Calbiochem®
别名:
DUB抑制剂V，PR-619, UCH-L3抑制剂II，UCH-L5/UCH37抑制剂III，USP5抑制剂II，USP7抑制剂I，USP9X抑制剂II，USP14抑制剂IV，USP14抑制剂IV，USP47抑制剂I，2,6-二氨基吡啶-3,5-双（硫氰酸盐），3,5-二硫氰基吡啶-2,6-二胺，PR619，UC
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关于此项目
经验公式（希尔记法）:
C7H5N5S2
分子量:
223.28
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥99% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
DUB抑制剂V，PR-619, The DUB Inhibitor V, PR-619 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Quality Level
assay
≥99% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
light beige to yellow
solubility
DMSO: 50 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
一种细胞渗透性吡啶胺类广谱DUB抑制剂，其已知靶标包括ATXN3、BAP1、JOSD2、OTUD5、UCH-L1、UCH-L3、UCH-L5/UCH37、USP1、2、4、5、7、8、9X、10、14、15、16、19、20、22、24、28、47、48、VCIP135、YOD1，以及deISGylase PLpro、deNEDDylase DEN1和deSUMOlyase SENP6。PR-619和P22077（目录号662142）均显示以剂量和时间依赖性方式（20至150 µM；0.5至20 h）增加HEK293T细胞中的整体蛋白多聚泛素化，然而P22077暴露主要导致K48连接的富集，而PR619处理导致K48和K63连接的多聚亚基链的上调。
Packaging
用惰性气体包装
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
WGK 3
相关内容
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 662141-25MG | 04055977261240 |