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Merck
CN

8.07491

聚乙二醇

greener alternative

6000, for synthesis

别名:

聚(乙二醇), 聚乙二醇,聚环氧乙烷,聚氧乙烯,PEG 6000, PEG

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关于此项目

线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.22
EC Index Number:
500-038-2
UNSPSC Code:
13111021
MDL number:
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vapor pressure

<0.01 hPa ( 20 °C)

Quality Level

form

solid

autoignition temp.

420 °C

potency

28000 mg/kg LD50, oral (Rat), >20000 mg/kg LD50, skin (Rabbit)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

pH

5-7 (20 °C, 100 g/L in H2O)

mp

58-63 °C

transition temp

flash point 270 °C

density

1.2 g/cm3 at 20 °C

greener alternative category

storage temp.

2-30°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

聚乙二醇(PEG)是一种人工合成的亲水性生物相容聚合物,在PEG化、表面共轭、纳米颗粒涂层和水凝胶交联等方面具有广泛应用。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

聚乙二醇6000是一种非离子表面活性剂,可用作结构导向剂以制备介孔γ-Al2O3。PEG 6000可诱导薄水铝石纳米颗粒形成片状结构形态,具有更高的比表面积、更大的孔体积和孔径等纹理性能。它也用于药物制剂中,以提高水溶性差的药物分子的溶解速度。PEG-6000也可用于选择性沉淀法纯化核酸。该方法比常用的色谱纯化方法更经济高效,且速度快。

Analysis Note

熔程(下限值): ≥ 59 °C
熔程(上限值): ≤ 64 °C
羟值:16 - 23
平均分子量:5000 - 7000
同一性(IR):通过测试


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup



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S Biswal et al.
AAPS PharmSciTech, 9(2), 563-570 (2008-05-07)
The aim of the present study was to enhance the dissolution rate of gliclazide using its solid dispersions (SDs) with polyethylene glycol (PEG) 6000. The phase solubility behavior of gliclazide in presence of various concentrations of PEG 6000 in 0.1



全球贸易项目编号

货号GTIN
807491100004022536395968
807491500004022536395975
807491905004022536395999
807491905104022536864716