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Merck
CN

8.20128

Saccharin

for synthesis

别名:

Saccharin

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关于此项目

经验公式(希尔记法):
C7H5NO3S
化学文摘社编号:
分子量:
183.18
UNSPSC Code:
12352115
EC Index Number:
201-321-0
NACRES:
NA.22
MDL number:
Assay:
≥98.0% (acidimetric)
Form:
crystals
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Quality Level

assay

≥98.0% (acidimetric)

form

crystals

mp

228-230 °C

storage temp.

2-30°C

SMILES string

[S]1(=O)(=O)NC(=O)c2c1cccc2

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

Application


  • Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).

  • Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).


Analysis Note

Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
820128025004022536452579
820128100004022536452586
820128500004022536879949