Quality Level
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
chicken, mouse, human, rat
should not react with
bovine
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... NGF(4803)
Immunogen
Mouse nerve growth factor-beta purified from salivary glands.
Application
Anti-Nerve Growth Factor-β Antibody detects level of Nerve Growth Factor-β & has been published & validated for use in ELISA, WB, IH.
Immunohistochemistry: 1-2 μg/mL (see suggested protocol).
Immunoblotting: 1-2 μg/mL
Inhibition of biological activity: 1-2 μg/mL
BIOLOGICAL ACTIVITY: This antibody will completely inhibit the survival and neurite outgrowth actions of mouse NGF in chicken dorsal root ganglion neurons in vitro.
ELISA: 1-2 μg/mL
Use neat for in vivo animal studies.
Optimal working dilutions must be determined by the end user.
Immunoblotting: 1-2 μg/mL
Inhibition of biological activity: 1-2 μg/mL
BIOLOGICAL ACTIVITY: This antibody will completely inhibit the survival and neurite outgrowth actions of mouse NGF in chicken dorsal root ganglion neurons in vitro.
ELISA: 1-2 μg/mL
Use neat for in vivo animal studies.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
Biochem/physiol Actions
Nerve growth factor-beta (NGF). Less than 1% cross-reactivity with recombinant human NT3, NT4 and BDNF by ELISA.
Physical form
Purified immunoglobulin. Lyophilized from PBS. Contains no preservative. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).
Format: Purified
Preparation Note
Maintain at -20 to -70°C in undiluted aliquots for up to one year after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. Glycerol (1:1) may be added for additional stability. Avoid repeated freeze/thaw cycles.
Other Notes
Replaces: 04-1119
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Expression of nerve growth factor is upregulated in the rat thymic epithelial cells during thymus regeneration following acute thymic involution.
Hee-Woo Lee, Sung-Min Kim, Na-Ri Shim, Soo-Kyung Bae, Il-Gun Jung, Jong-Young Kwak et al.
Regulatory Peptides null
Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia.
M Goedert et al.
Brain research, 148(1), 264-268 (1978-06-09)
Patricia Cassina et al.
Journal of neurochemistry, 93(1), 38-46 (2005-03-19)
Fibroblast growth factor-1 (FGF1 or acidic FGF) is highly expressed in motor neurons. FGF-1 is released from cells by oxidative stress, which might occur from SOD-1 aberrant function in amyotrophic lateral sclerosis (ALS). Although FGF-1 is known to be neuroprotective
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB1526SP | 04053252581045 |