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Merck
CN

AB15412

Anti-MAP1LC3A antibody

CHEMICON®, rabbit polyclonal

别名:

Microtubule-associated proteins 1A/1B light chain 3A, MAP1A/1B LC3 A, MAP1 LC3, LC3 A

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
rat, human
Application:
ICC, IHC, WB
Citations:
6
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产品名称

Anti-MAP1LC3 A Antibody, serum, Chemicon®

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MAP1LC3A(84557)

General description

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The human MAP1LC3 protein is homologous with the rat Map1LC3 and with yeast APG8. These proteins are likely to be involved in the formation of autophagosomal vacuoles (autophagosomes).

Immunogen

Synthetic peptide corresponding to a region within the N-terminus of human MAP1LC3 A protein.

Application

Western blot: 1:200-1:1,000
Immunocytochemistry: 1:200-1:1,000
Immunohistochemistry: 1:200-1:1,000
Optimal working dilutions must be determined by end user.
Anti-MAP1LC3 A Antibody is an antibody against MAP1LC3 A for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Biochem/physiol Actions

MAP1LC3 A [Microtubule-associated proteins 1A/1B light chain 3A, MAP1A/1B LC3 A, MAP1 LC3, LC3 A].

Physical form

Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
Serum

Preparation Note

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Other Notes

Replaces: MABC176

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids



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E Couve et al.
Journal of dental research, 90(4), 523-528 (2011-01-08)
Odontoblasts are long-lived post-mitotic cells in the dental pulp, whose function is to form and maintain dentin. The survival mechanisms that preserve the viability of terminally differentiated odontoblasts during the life of a healthy tooth have not been described. In
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation.
Iwata, Atsushi, et al.
Proceedings of the National Academy of Sciences of the USA, 102, 13135-13140 (2005)
Hua He et al.
The Journal of biological chemistry, 278(31), 29278-29287 (2003-05-13)
The molecular machinery required for autophagy is highly conserved in all eukaryotes as seen by the high degree of conservation of proteins involved in the formation of the autophagosome membranes. Recently, both yeast Apg8p and its rat homologue Map1lc3 were



全球贸易项目编号

货号GTIN
AB1541204053252678974