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Merck
CN

AB15467P

Anti-ARG3.1 Antibody

Chemicon®, from rabbit

别名:

Growth factor ARC, Activity regulated cytoskeleton

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC
Citations:
1
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NOL3(8996)

General description

Arc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus.

Immunogen

Synthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein.

Application

Anti-ARG3.1 Antibody detects level of ARG3.1 & has been published & validated for use in IH.
Immunohistochemistry: 1:200-1:1,000

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Synapse & Synaptic Biology

Biochem/physiol Actions

ARG3.1 [Growth factor ARC, Activity regulated cytoskeleton]

Physical form

Format: Purified
Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Preparation Note

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

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Jason D Shepherd et al.
Neuron, 52(3), 475-484 (2006-11-08)
Homeostatic plasticity may compensate for Hebbian forms of synaptic plasticity, such as long-term potentiation (LTP) and depression (LTD), by scaling neuronal output without changing the relative strength of individual synapses. This delicate balance between neuronal output and distributed synaptic weight



全球贸易项目编号

货号GTIN
AB15467P04053252744099