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Merck
CN

AB1952P

Anti-Integrin beta 1 (CD29) Antibody

CHEMICON®, rabbit polyclonal

别名:

CD29

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
human, rat, pig, mouse
Application:
IP, WB
Citations:
12
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产品名称

Anti-Integrin β1 Antibody, cytosolic, Chemicon®, from rabbit

biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, pig, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB1(3688)

General description

130kDa

Immunogen

Epitope: cytosolic
Synthetic peptide corresponding to the C-terminus of human integrin beta 1 (a.a. CTTVVNPKYEGK)

Application

Detect Integrin β1 using this Anti-Integrin β1 Antibody, cytosolic validated for use in IP & WB.
Western blot: 1-2μg/mL for detection in whole cell lysate. The antibody is effective against reduced (MW = 130kDa) and non-reduced (MW = 110kDa) proteins.

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reactive with human, mouse, and rat integrin beta-1, as confirmed by western blot. Not reactive with other integrins.

Physical form

Format: Purified
Protein A Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.

Analysis Note

Control
U251 cell line Skin (Basement Membrane)

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

12 - Non Combustible Liquids



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N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1.
Tomoya Isaji,Yuya Sato,Tomohiko Fukuda,Jianguo Gu
The Journal of Biological Chemistry null
Jean-Baptiste Oudart et al.
Cell adhesion & migration, 15(1), 215-223 (2021-07-27)
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4
Xiaoming Bai et al.
Scientific reports, 4, 6538-6538 (2014-10-08)
Prostaglandin E2 (PGE2) has been implicated in cell invasion in hepatocellular carcinoma (HCC), via increased β1-integrin expression and cell migration; however, the mechanism remains unclear. PGE2 exerts its effects via four subtypes of the E prostanoid receptor (EP receptor 1-4).



全球贸易项目编号

货号GTIN
AB1952P04053252621383