biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SLC16A1(6566)
Immunogen
人MCT1 C末端附近的15个氨基酸肽序列(Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999)。
Application
研究子类别
离子通道 & 转运体
离子通道 & 转运体
研究类别
神经科学
神经科学
蛋白质印迹:使用ECL为1-5μg/mL
ELISA:1:10,000-1:100,000,每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
ELISA:1:10,000-1:100,000,每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
该抗单羧酸转运蛋白1抗体经验证可用于ELISA,WB检测单羧酸转运蛋白1。
Biochem/physiol Actions
可识别人单羧酸转运蛋白1(MCT1)。免疫原与MCT2-8没有明显的序列同源性。
Physical form
亲和纯化的免疫球蛋白。 含0.1%BSA的PBS液体。
Preparation Note
收到货后,在-20°C下以未稀释等分试样可保存长达6个月。应避免反复冻/融循环。
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats.
Gerhart, D Z, et al.
The American Journal of Physiology, 273, E207-E213 (1997)
S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells.
Diers, AR; Broniowska, KA; Chang, CF; Hill, RB; Hogg, N
Free radical biology & medicine null
Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas.
Vera Miranda-Gonçalves et al.
Oncotarget, 7(29), 46335-46353 (2016-06-23)
Glioblastomas (GBM) present a high cellular heterogeneity with conspicuous necrotic regions associated with hypoxia, which is related to tumor aggressiveness. GBM tumors exhibit high glycolytic metabolism with increased lactate production that is extruded to the tumor microenvironment through monocarboxylate transporters
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB3538P | 04053252730528 |