biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... ADRB3(155)
Immunogen
A 19 aa sequence at the C-terminus of the human B3AR, splce variant 3 (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993). Control peptide is available under catalog number AG388.
Application
Anti-Adrenergic Receptor Antibody, β 3 detects level of Adrenergic Receptor & has been published & validated for use in ELISA, IH & WB.
Western blot: 1-10 μg/mL using Chemiluminescence technique
ELISA: 1:10,000 - 100,000
Immunohistochemistry: 2-20 μg in formaldehyde fixed tissue.
Optimal working dilutions must be determined by end user.
ELISA: 1:10,000 - 100,000
Immunohistochemistry: 2-20 μg in formaldehyde fixed tissue.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Human beta 3 adrenergic receptor (B3AR) is a member of the G-protein coupled receptor superfamily. They typically contain 7 transmembrane domains (Barak et al., 1995) Human B3AR is 408 aa membrane protein (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993).
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Stimulation of the ADRB3 adrenergic receptor induces relaxation of human placental arteries: influence of preeclampsia.
Rouget, C; Barthez, O; Goirand, F; Leroy, MJ; Breuiller-Fouche, M; Rakotoniaina et al.
Biology of reproduction null
Rodent and human beta 3-adrenergic receptor genes contain an intron within the protein-coding block.
J G Granneman et al.
Molecular pharmacology, 42(6), 964-970 (1992-12-01)
DNA blot analysis of the cloned rat beta 3-adrenergic receptor gene revealed unexpected restriction enzyme cleavage sites that suggested the presence of one or more introns near the end of the coding block. This region of the rat gene was
{beta}1, {beta}2, {beta}3-Adrenoceptors and NHERF1 Expression in Human Bronchi and Their Modifications in Cystic Fibrosis.
Bossard F, Silantieff E, Lavazais-Blancou E, Robay A, Sagan C, Rozec B, Gauthier C
American Journal of Respiratory Cell and Molecular Biology null
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB5122 | 04053252618734 |