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Merck
CN

AB5122

Anti-Adrenergic Receptor Antibody, β 3

Chemicon®, from rabbit

别名:

Anti-Anti-B3AR, Anti-Anti-GPCR

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
15
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ADRB3(155)

Immunogen

A 19 aa sequence at the C-terminus of the human B3AR, splce variant 3 (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993). Control peptide is available under catalog number AG388.

Application

Anti-Adrenergic Receptor Antibody, β 3 detects level of Adrenergic Receptor & has been published & validated for use in ELISA, IH & WB.
Western blot: 1-10 μg/mL using Chemiluminescence technique

ELISA: 1:10,000 - 100,000

Immunohistochemistry: 2-20 μg in formaldehyde fixed tissue.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Human beta 3 adrenergic receptor (B3AR) is a member of the G-protein coupled receptor superfamily. They typically contain 7 transmembrane domains (Barak et al., 1995) Human B3AR is 408 aa membrane protein (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Stimulation of the ADRB3 adrenergic receptor induces relaxation of human placental arteries: influence of preeclampsia.
Rouget, C; Barthez, O; Goirand, F; Leroy, MJ; Breuiller-Fouche, M; Rakotoniaina et al.
Biology of reproduction null
J G Granneman et al.
Molecular pharmacology, 42(6), 964-970 (1992-12-01)
DNA blot analysis of the cloned rat beta 3-adrenergic receptor gene revealed unexpected restriction enzyme cleavage sites that suggested the presence of one or more introns near the end of the coding block. This region of the rat gene was
{beta}1, {beta}2, {beta}3-Adrenoceptors and NHERF1 Expression in Human Bronchi and Their Modifications in Cystic Fibrosis.
Bossard F, Silantieff E, Lavazais-Blancou E, Robay A, Sagan C, Rozec B, Gauthier C
American Journal of Respiratory Cell and Molecular Biology null



全球贸易项目编号

货号GTIN
AB512204053252618734