biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Rtn4(68585)
General description
Theoretical MW is approx. 126 kDa however literature reports observed molecular weight to be 205 kDa to 220 kDa
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified
Application
Anti-NOGO A Antibody detects level of NOGO A & has been published & validated for use in WB.
Biochem/physiol Actions
Cat. # AB5888 is specific to NOGO A. It does not recognize NOGO B or NOGO C.
Reactivity with other species has not been tested.
Analysis Note
Routinely tested on mouse brain lysate
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Feng Tan et al.
Experimental and therapeutic medicine, 16(6), 4943-4950 (2018-12-14)
Electroacupuncture (EA) may stimulate neurogenesis in animal models of ischemic stroke; however, the associated mechanisms are not clear. The present study aimed to evaluate the neurogenesis efficacy of EA on ischemic stroke and the underlying associated mechanisms. A model of
Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosis.
Anna Jurewicz,Mariola Matysiak,Cedric S Raine,Krzysztof Selmaj
Neurology null
Ryan L O'Hare Doig et al.
BMC neuroscience, 18(1), 62-62 (2017-08-16)
Following partial injury to the central nervous system, cells beyond the initial injury site undergo secondary degeneration, exacerbating loss of neurons, compact myelin and function. Changes in Ca2+ flux are associated with metabolic and structural changes, but it is not
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB5888 | 04053252618680 |