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Merck
CN

AB9904

QKI-5抗体

serum, Chemicon®

别名:

Quaking Protein

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
7
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... QKI(9444)

General description

QKI 是一种RNA结合蛋白,在髓鞘形成中起主导作用。通过调节pre-mRNA剪接、mRNA输出、mRNA稳定性和蛋白质翻译起作用。它通过可变剪接调节。
~40 kDa

Immunogen

来自小鼠QKI-5的合成肽。

Application

可使用这种QKI-5抗体检测QKI-5,该抗体经验证可用于IP & WB。
研究子类别
发育神经科学

RNA结合蛋白(RBP)
研究类别
神经科学

Biochem/physiol Actions

QKI-5 (Quaking 蛋白)该抗体识别~40 kDa蛋白。

Physical form

液体。
血清

Preparation Note

自收到之日起,在 -20°C 以未稀释的等分试样可保存 12 个月。应避免反复冻/融循环。

Analysis Note

对照
阳性对照:神经胶质细胞、星形胶质细胞和少突胶质细胞

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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相关内容

All eukaryotic organisms require tight regulation of gene expression for complex processes such as development, differentiation, cell specification, and responses to environmental stimuli. Many genes are regulated post-transcriptionally, in addition to transcriptional mechanisms of gene regulation. RNA-binding proteins (RBPs) are essential for post-transcriptional gene regulation, linking transcription and translation in many processes including transcription, splicing, export, rate of translation and turnover. In all of these events, RBPs coordinate regulation of the amount of protein produced from mRNA transcripts.


Fang Wang et al.
Cell research, 27(3), 416-439 (2017-03-01)
MicroRNA (miRNA) biogenesis is finely controlled by complex layers of post-transcriptional regulators, including RNA-binding proteins (RBPs). Here, we show that an RBP, QKI5, activates the processing of primary miR-124-1 (pri-124-1) during erythropoiesis. QKI5 recognizes a distal QKI response element and
Xingyu Yang et al.
Journal of cellular and molecular medicine, 25(12), 5655-5670 (2021-05-05)
Preeclampsia (PE) is characterized by placental ischemia and hypoxia, resulting in abnormal casting of the uterine spiral artery, which is mainly caused by insufficient trophoblastic cell infiltration. A reduction in levels of growth factor-based signalling via Neuropilin-1 (NRP1) has been
Benjamin Rauwel et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 35(4), 753-765 (2019-12-14)
Increased osteoclastogenesis is a common feature of bone erosion, notably in osteoporosis but also in inflammatory diseases such as rheumatoid arthritis (RA) and osteoarticular infections. Human cytomegalovirus (HCMV) infection has been described to impair monocyte differentiation into macrophages and dendritic



全球贸易项目编号

货号GTIN
AB990404053252742255