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Merck
CN

ABD12

抗醛脱氢酶1(ALDH1A1)抗体

from rabbit, purified by affinity chromatography

别名:

aldehyde dehydrogenase 1 family, member A1, ALDH class 1, Aldehyde dehydrogenase, cytosolic, retinaldehyde dehydrogenase 1, Aldehyde dehydrogenase family 1 member A1, retinal dehydrogenase 1, acetaldehyde dehydrogenase 1, aldehyde dehydrogenase 1, solubl

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

packaging

antibody small pack of 25 μg

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... ALDH1A1(216)

General description

醛脱氢酶 1A1(ALDH1A1)也称为视网膜脱氢酶 1。人们认为它是视黄醇向视黄酸的主要转化酶,这在细胞间信号转导中非常重要。ALDH1A1 也可能参与抑制胰腺癌细胞的侵袭。更具体地说,ALDH1A1 可通过破坏类维生素 A 信号传导来调节造血干细胞的分化。
观测值〜54 kDa

Immunogen

对应于人醛脱氢酶 1 的 KLH 偶联的线性肽。

Application

研究类别
干细胞研究
该抗醛脱氢酶 1(ALDH1A1)抗体经过验证可用在 WB 中检测醛脱氢酶 1(ALDH1A1)。

Biochem/physiol Actions

其他同源性:大鼠和小鼠(具有 91% 的序列同源性)。

Physical form

亲和纯化
在含 0.1 M Tris-甘氨酸(pH 7.4),150 mM NaCl 和 0.05% 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。

Preparation Note

自收到之日起,在 2-8°C 条下可稳定保存 1 年。

Analysis Note

对照
HepG2 细胞裂解液
通过蛋白质印迹对 HepG2 细胞裂解液进行了评估。

蛋白质印迹分析:0.05 µg/mL 的该抗体在 10 µg HepG2 细胞裂解液中检测到醛脱氢酶 1。

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Natalia Ninkina et al.
Neurobiology of aging, 91, 76-87 (2020-04-01)
The etiology and pathogenesis of Parkinson's disease (PD) are tightly linked to the gain-of-function of α-synuclein. However, gradual accumulation of α-synuclein aggregates in dopaminergic neurons of substantia nigra pars compacta (SNpc) leads to the depletion of the functional pool of
Yi Sui et al.
British journal of cancer, 125(7), 1003-1015 (2021-07-12)
Metastasis is the major cause of treatment failure and cancer-related deaths in prostate cancer (PCa) patients. Our previous study demonstrated that a CD44+ subpopulation isolated from PCa cells or tumours possesses both stem cell properties and metastatic potential, serving as
Angelica R Harper et al.
PloS one, 10(3), e0122008-e0122008 (2015-03-21)
Retinaldehyde dehydrogenase 2 (RALDH2) has been implicated in regulating all-trans-retinoic acid (atRA) synthesis in response to visual signals in animal models of myopia. To explore the potential role of retinaldehyde dehydrogenase (RALDH) enzymes and atRA in human postnatal ocular growth



全球贸易项目编号

货号GTIN
ABD12-25UG04054839337376