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Merck
CN

CBL458P

Anti-CD49f Antibody, clone 4F10, Phycoerythrin conjugated

clone 4F10, Chemicon®, from mouse

别名:

Integrin alpha6

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
PE
Clone:
4F10, monoclonal
Application:
FACS
Citations:
8
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biological source

mouse

Quality Level

conjugate

PE

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

4F10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable

isotype

IgG2b

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA6(3655)

Immunogen

Cell line SW/222 (Human colorectal carcinoma)

Application

Detect CD49f using this Anti-CD49f Antibody, clone 4F10, Phycoerythrin conjugated validated for use in FC.
Immunohistological studies on frozen sections

Immunoprecipitation of the laminin receptor

Flow Cytometry

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

This antibody is specific to the integrin alpha6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha6 chain, which consists of a single disulphide linked 120 kDa subunit and a small doublet subunit of 25/30 kDa, is non covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha6/beta1 complex or with integrin beta4 chain (alpha6/beta4).

The antigen is also expressed on platelets, monocytes, thymocytes and T lymphocytes.

FUSION PARTNER: NS1 myeloma cell line

Physical form

The conjugate is supplied in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.

Preparation Note

Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C for up to one year.

Other Notes

Replaces: MAB2254E

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.
James C Garbe,Francois Pepin,Fanny A Pelissier,Klara Sputova,Agla J Fridriksdottir et al.
Cancer Research null
Expression of integrin subunits in the human infant breast correlates with morphogenesis and differentiation
Anbazhagan, R. et al.
The Journal of Pathology, 176 (3), 227-232 (1995)
Cell adhesion molecules in oesophageal epithelium
Dobson, H. et al.
Gut, 35, 1343-1347 (1994)



全球贸易项目编号

货号GTIN
CBL458P04053252737831