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Merck
CN

DX1726

N,N-二甲基甲酰胺

OmniSolv®

别名:

DMF, NSC 5356

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关于此项目

线性分子式:
HCON(CH3)2
化学文摘社编号:
分子量:
73.09
EC Index Number:
200-679-5
UNSPSC Code:
12352111
Beilstein/REAXYS Number:
605365
MDL number:
eCl@ss:
39031202
Assay:
≥99.9% (GC)
Technique(s):
HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable
Bp:
153 °C (lit.)
Vapor pressure:
2.7 mmHg ( 20 °C)
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vapor density

2.5 (vs air)

Quality Level

vapor pressure

2.7 mmHg ( 20 °C)

product line

OmniSolv®

assay

≥99.9% (GC)

form

liquid

autoignition temp.

833 °F

shelf life

24 mo.

expl. lim.

15.2 %

technique(s)

HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable

impurities

<0.05% Water

evapn. residue

<5 ppm

color

APHA: 10

refractive index

n20/D 1.430 (lit.)

pH

7 (20 °C, 200 g/L in H2O)

bp

153 °C (lit.)

mp

−61 °C (lit.)

transition temp

flash point 57.5 °C

density

0.944 g/mL (lit.)

UV cutoff

≤268 nm

UV absorption

λ: 268 nm Amax: ≤1.00, λ: 270 nm Amax: ≤0.75, λ: 275 nm Amax: ≤0.30, λ: 295 nm Amax: ≤0.07, λ: 310 nm Amax: ≤0.03, λ: 340 nm Amax: ≤0.01

shipped in

ambient

storage temp.

room temp

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

General description

N,N - Dimethylformamide (DMF) is a highly effective polar aprotic solvent for a wide range of compounds. This is due to its ability to interact effectively with different compounds. DMF can function as both an electrophilic and nucleophilic agent, and it can provide various key intermediates that mediate chemical reactions.

Application

N,N-Dimethylformamide (DMF) is used

  • As a solvent in the Wittig reaction for synthesizing α-hydroxy amides.
  • In the preparation of the Vilsmeier reagent when treated with phosphorus oxychloride or other acid chlorides, which is utilized for formylating, halogenating, and dehydroxylating reactions.
  • As a solvent in the synthesis of alkyl halides from alcohols.
  • As a co-solvent to examine the relationship between medium polarity and drug solubility.
多种疏水性有机化合物的溶剂。
OmniSolv®

Packaging

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!
is packaged in 1L amber glass bottle
is packaged in 4L amber glass bottle
is packaged in 4L polycoated glass bottle

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Assay (GC): 99.9% min
Color (APHA): 10 max
Evaporation residue: 5ppm max
Expiration date: 24 months
Filtered through 0.2 m filter: To pass test
Form: Clear liquid
Infrared Spectrum: Conforms to standard
Titrable acid: eq/g
Titrable base: eq/g
UV Abs. at 268 nm: 1.00AU max
UV Abs. at 270 nm: 0.75AU max
UV Abs. at 275 nm: 0.30AU max
UV Abs. at 295 nm: 0.07AU max
UV Abs. at 310 nm: 0.03AU max
UV Abs. at 340 nm: 0.01AU max
UV Cut-off: 268nm max
Water (H2O): 0.05% max

Legal Information

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

135.5 °F - closed cup

flash_point_c

57.5 °C - closed cup

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全球贸易项目编号

货号GTIN
DX1726-604061839419537
DX1726-104061839419483
DX1726-3104061839419490
DX1726-NP2004061839419544
DX1726P-104061839419582