EZHS42
Human Amyloid β42 ELISA Kit
measures and quantifies Amyloid β42 levels in 50 μL CSF, cell culture supernatent or plasma
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UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84
Gene information:
human ... APP(351)
Input:
sample type plasma (K2 EDTA)
sample type serum
sample type cerebrospinal fluid (CSF)
sample type serum
sample type cerebrospinal fluid (CSF)
Assay range:
sensitivity: 8.0 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
Species reactivity:
human
Storage temp.:
2-8°C
Shipped in:
wet ice
产品名称
High Sensitivity Human Amyloid β42 ELISA,
Quality Level
description
This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
species reactivity
human
packaging
kit of 1 × 96 wells
parameter
50 μL sample volume (Overnight assay)
assay range
sensitivity: 8.0 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
technique(s)
ELISA: suitable
input
sample type plasma (K2 EDTA)
sample type serum
sample type cerebrospinal fluid (CSF)
application(s)
research use
detection method
colorimetric (450nm/590nm)
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... APP(351)
General description
Amyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s High Sensitivity Human Amyloid β42 ELISA kit is used for the measurement of Amyloid β42 in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Alzheimer′s Disease
Alzheimer′s Disease
This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
This assay requires 50 µl of sample and is an overnight assay.
Used to detect/quantify: Amyloid β42
Biochem/physiol Actions
The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.
Preparation Note
Components in the kit can be stored up to 2 weeks at 2-8°C
Other Notes
Please contact Technical Service for linearity of dilution.
Disclaimer
For research use only. Not for use in diagnostic procedures.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 3
法规信息
新产品
此项目有
Teresa Niccoli et al.
Current biology : CB, 26(17), 2291-2300 (2016-08-16)
Glucose hypometabolism is a prominent feature of the brains of patients with Alzheimer's disease (AD). Disease progression is associated with a reduction in glucose transporters in both neurons and endothelial cells of the blood-brain barrier. However, whether increasing glucose transport
Kendra L Puig et al.
Journal of Alzheimer's disease : JAD, 44(4), 1263-1278 (2014-11-20)
Alzheimer's disease (AD) is a neurodegenerative disorder histologically characterized by amyloid-β (Aβ) protein accumulation and activation of associated microglia. Although these features are well described in the central nervous system, the process and consequences of Aβ accumulation in the enteric
Loukia Katsouri et al.
Neurobiology of aging, 34(4), 1105-1115 (2012-10-16)
Noradrenergic deficits have been described in the hippocampus and the frontal cortex of Alzheimer's disease brains, which are secondary to locus coeruleus degeneration. Locus coeruleus is the brain stem nucleus responsible for synthesis of noradrenaline and from where all noradrenergic
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| 货号 | GTIN |
|---|---|
| EZHS42 | 04053252732133 |