FCMAB110P
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate
clone 10H11.E12, from mouse, PE
别名:
A-T, mutated
AT mutated
TEL1, telomere maintenance 1, homolog
ataxia telangiectasia mutated
ataxia telangiectasia mutated (includes complementation groups A, C and D)
ataxia telangiectasia mutated protein
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Species reactivity:
rat, mouse, human
Conjugate:
PE
Application:
FACS
Citations:
3
biological source
mouse
Quality Level
conjugate
PE
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
10H11.E12, monoclonal
species reactivity
rat, mouse, human
technique(s)
flow cytometry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer1981)
Gene Information
human ... ATM(472)
General description
N-terminal c-Myc, GST-tagged, recombinant human Cardiac Troponin I full length, expressed by baculovirus in Sf21 insect cells. Purified using glutathione sepharose.
~370 kDa Calculated
Immunogen
Epitope: Phosphorylated at and around Ser1981
KLH-conjugated, synthetic peptide corresponding to human ATM phosphorylated at Ser1981.
Application
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate detects level of phospho-ATM (Ser1981) & has been published & validated for use in FC.
Biochem/physiol Actions
Antibody recognizes ATM phosphorylated at Ser1981.
Predicted to cross-react with rat based on sequence homology
Physical form
Purified mouse monoclonal IgG1κ conjugated to phycoerythrin in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.
Analysis Note
Control
Irradiated HeLa cells
Irradiated HeLa cells
Evaluated by Flow Cytometry with HeLa cells.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Yiting Lim et al.
International journal of radiation oncology, biology, physics, 84(3), 800-806 (2012-03-27)
We have previously shown that the antimalarial agent chloroquine can abrogate the lethal cellular effects of low-dose-rate (LDR) radiation in vitro, most likely by activating the ataxia-telangiectasia mutated (ATM) protein. Here, we demonstrate that chloroquine treatment also protects against lethal doses
null
S Masneri et al.
Stem cell research, 41, 101596-101596 (2019-11-02)
Using a Sendai Virus based vector delivering Yamanaka Factors, we generated induced Pluripotent Stem Cells (iPSCs) from peripheral blood mononuclear cells of a patient affected by Ataxia Telangiectasia (AT), caused by a novel homozygous deletion in ATM, spanning exons 5-7.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| FCMAB110P | 04053252405143 |