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Merck
CN

IM1014

Anti-Matriptase/MT-SP1 Rabbit pAb

liquid, Calbiochem®

别名:

Anti-Membrane-Type Serine Protease 1, Anti-Suppressor of Tumorgenicity 14

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
Citations:
6
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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

dilution

(Immunoblotting (1:500-1:2000)
Immunoprecipitation (5-20 µg/mg lysate))

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... ST14(6768)

General description

Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~75 kDa matriptase protein.
Recognizes the ~75 kDa matriptase protein in MCF-7 cells.
This Anti-Matriptase/MT-SP1 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of Matriptase/MT-SP1.

Immunogen

Human
a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase

Application


Immunoblotting (1:500-1:2000)
Immunoprecipitation (5-20 g/mg lysate)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In Tris-citrate/phosphate buffer, pH 7.0-8.0.

Preparation Note

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.

Analysis Note

Positive Control
MCF-7 cells

Other Notes

Antibody should be titrated for optimal results in individual systems.
Santin, A.D., et al. 2003. Cancer98, 1898.
Takeuchi, T., et al. 2000. J. Biol. Chem.275, 26333.
Lin, C.Y., et al. 1999. J. Biol. Chem.274, 18231.
Takeuchi, T., et al. 1999. Proc. Natl. Acad. Sci. USA96, 11054.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary.
Godiksen, et al.
The Biochemical Journal, 413, 251-259 (2020)
Growth differentiation factor-15 upregulates interleukin-6 to promote tumorigenesis of prostate carcinoma PC-3 cells.
Tsui, et al.
Journal of Molecular Endocrinology, 49, 153-163 (2012)
Sine Godiksen et al.
PloS one, 8(10), e77146-e77146 (2013-11-10)
Matriptase is a member of the family of type II transmembrane serine proteases that is essential for development and maintenance of several epithelial tissues. Matriptase is synthesized as a single-chain zymogen precursor that is processed into a two-chain disulfide-linked form



全球贸易项目编号

货号GTIN
IM1014-50UG04055977228175