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Merck
CN

MAB1945

Anti-Vitronectin Antibody, clone BV2

clone BV2, Chemicon®, from mouse

别名:

Serum spreading factor, S-protein

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
BV2, monoclonal
Application:
ELISA, FACS, IHC, IP, WB
Citations:
44
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Quality Level

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

BV2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... VTN(7448)

Immunogen

Purified human plasma vitronectin (Preissner, 1985).

Application

Anti-Vitronectin Antibody, clone BV2 is an antibody against Vitronectin for use in ELISA, FC, IP, WB, IH.
ELISA

Immunoprecipitation

Western blot

Immunohistochemistry/immunofluorescence

Inhibits endothelial cell adhesion and spreading on vitronectin-coated surfaces.

Flow Cytometry

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Biochem/physiol Actions

Human vitronectin. Specificity determined by ELISA and immunoprecipitation of I125 labeled vitronectin purified from plasma (Zanetti et al., 1994). The antibody reacts with vitronectin both in its native and denatured form.

Physical form

Format: Purified
Purified immunoglobulin by Protein A chromatography. Liquid in PBS containing 0.05% sodium azide and 0.1% BSA.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane
Zanetti, A. et al.
Blood, 84, 1116-1123 (1994)
Complement activation and inflammatory processes in Drusen formation and age related macular degeneration.
L V Johnson, W P Leitner, M K Staples, D H Anderson
Experimental Eye Research null
R J Falk et al.
The American journal of pathology, 127(1), 182-190 (1987-04-01)
The S protein (S) binds to the attack complex of complement (C5b-9) in plasma preventing cytolysis. Using immunofluorescence microscopy, the authors determined the distribution of S in human renal tissue and its relationship to C5b-9, immunoglobulins, C3, albumin, and fibronectin.



全球贸易项目编号

货号GTIN
MAB194504053252317453