MAB1974
Anti-Integrin beta 3 (ITGB3/CD61) Antibody
CHEMICON®, mouse monoclonal, BB10
别名:
CD61
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
BB10, monoclonal
Species reactivity:
human
Application:
ICC, IHC, WB
Citations:
11
产品名称
Anti-Integrin β3 Antibody, clone BB10, clone BB10, Chemicon®, from mouse
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BB10, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG1
suitability
not suitable for immunohistochemistry (Paraffin)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB3(3690)
Immunogen
Partially purified platelet glycoprotein IIb/lIIa complex.
Application
Anti-Integrin β3 Antibody, clone BB10 is an antibody against Integrin β3 for use in WB, IC, IH.
Immunoblotting: 1:1000 (Ylanne et al., 1988, 1990). The antibody is most effective when used against non-reduced samples.
immunohistochemistry (indirect immunofluorescence)1:200 - 1:400. (Ylanne et al., 1988).
Does not work on paraffin embedded sections.
Final working dilutions must be determined by end user.
immunohistochemistry (indirect immunofluorescence)1:200 - 1:400. (Ylanne et al., 1988).
Does not work on paraffin embedded sections.
Final working dilutions must be determined by end user.
Biochem/physiol Actions
Reacts with the beta-3 subunit of the integrin family, including GPIIIa of platelets. Recognized an extracellular epitope of beta-3.
Physical form
Format: Purified
Purified immunoglobulin. In PBS with 1% BSA and 0.1% sodium azide.
Preparation Note
Maintain between 2 and 8°C up to 12 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas.
Partheen, K; Levan, K; Osterberg, L; Claesson, I; Sundfeldt, K; Horvath, G
BMC Cancer null
Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells.
Ylanne, J, et al.
Blood, 76, 570-577 (1990)
Karolina Partheen et al.
International journal of cancer, 123(9), 2130-2137 (2008-08-19)
The mortality rate for patients with ovarian carcinomas is high and the available prognostic factors are insufficient. The use of biomarkers may contribute to better prediction and survival for these patients. We aimed to study the gene and protein expressions
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB1974 | 04053252265020 |