biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
P2A4, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ICAM1(3383)
Immunogen
IL-1beta activated HUVEC (human)
Application
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Anti-ICAM-1 Antibody, clone P2A4 is an antibody against ICAM-1 for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Human ICAM-1
Physical form
Format: Purified
Nonsterile liquid contains 0.2M phosphate buffer, 0.25M sodium chloride, and 0.1% sodium azide. Filtered through a 0.45 micron membrane filter.
Preparation Note
Maintain at +2-8°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
null
Akio Kawakami et al.
Circulation, 114(7), 681-687 (2006-08-09)
Activation of vascular endothelial cells (ECs) plays an important role in atherogenesis and plaque instability. Lipoproteins containing apolipoprotein CIII (apoCIII) predict coronary heart disease (CHD). We recently reported that apoCIII has a proinflammatory effect on human monocytes. In this study
Qiangjun Cai et al.
Arteriosclerosis, thrombosis, and vascular biology, 24(12), 2263-2270 (2004-10-02)
Vascular smooth muscle cells (VSMCs) may regulate monocyte functions within atherosclerotic lesions. We investigated the impact of VSMC/monocyte interactions on monocyte apoptosis and scavenger receptor CD36 expression, key events related to monocyte survival and differentiation. Serum deprivation significantly increased THP-1
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB2146 | 04053252660429 |